Antibacterial Activity of Marine derived Fungi Collected from South East Coast of Tamilnadu, India

Samuel P., Prince L, Prabakaran P


The present deals with an attempt to study the antibacterial activity of the marine fungi, collected from the south east coastal area of Tamilnadu, India. The fungal species were isolated on Potato Dextrose Agar Media amended with Streptomycin. Isolated five different fungal species were tested for its anti bacterial activity against 5 different human bacterial pathogens. The study revealed that, among the used fungal species, Geotrichum candidum was found to be active against all human pathogenic bacterial strains. Geotrichum candidum may lead to the discovery of pharmaceutically valuable products.


Keywords: Antibacterial activity, Geotrichum candidum, Potato Dextrose Agar, Streptomycin, Pharmaceutically valuable products.

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Natori, T., Morita, M., and Akimoto, K., 1994, Mauritians. 50:2771-2778.

Holler, U., Weight, A.D., Mathee, G.F., and Konie, G.M., 2000., Mycol. Res, 104:1354-1365.

Kohlmeyer, J., 1984. Tropical marine fungi marine ecology. 5:329-378.

Raghukumar, C., Sheelu, G., Loka Bharati, P.A., Nair, S., Mohandass, C., 2001. Georesour. Geotechnol. 19, 1–16.

Raghukumar, C., Raghukumar, S., Sheelu, G., Gupta, S.M., Nath, B. N., Rao, B.R., 2004. Deep-Sea Res. I 51, 1759–1768.

Barghoorn, E.S., Linder, D.H., 1944. Marine fungi: their taxonomy and biology. Farlowia 3, 395–467.

Johnson, T.W., Sparrow, F.K., 1961. . J. Cramer, Weinheim, Germany, 668 pp

Barnett, H.L., Hunter, B.B., 1972. Illustrated Genera of Imperfect Fungi, third ed. Burgess Publishing Co., Minneapolis, Minnesota, 241 pp.

Anisworth, G.C., Sparrow, F.K., Sussman, A.S., 1973a. The Fungi, an Advanced Treatise, vol. IVA. Academic Press, New York, 621 pp.

Anisworth, G.C., Sparrow, F.K., Sussman, A.S., 1973b. The Fungi, an Advanced Treatise, vol. IVB. Academic Press, New York, 504 pp.

Kohlmeyer J, Kohlmeyer E. Marine Mycology: The Higher Fungi. Academic Press; London, UK: 1979.

Kohlmeyer, J., Kohlmeyer, B.V., 1991. Illustrated key to the filamentous higher marine fungi. Bot. Mar. 34, 1–61.

Anisworth, G.C., 1971. Anisworth and Bisby’s Dictionary of the Fungi, sixth ed. Commonwealth Mycological Institute, Kew, Surrey, England.

Wagner., 1995. Analysis of quantitative phytochemicals for bioactive compounds in TLC methods. 221.

Maria, G.L.; Sridhar, K.R.; Raviraja, N.S. J. Agri. Tech. 2005, 1, 67-80.

Smetanina, O.F.; Kalinovsky, A.I.; Khudyakova, Y.V.; Pivkin, M.V.; Dmitrenok, P.S.; Fedorov, S.N.; Ji, H.; Kwak, J.Y. and Kuznetsova, T.A. (2007). Journal of Natural Products 70, 906-909.

Blunt, J. W.; Copp, B. R.; Munro, M. H. G.; Northcote, P. T. and Prinsep, M. R. (2006). Natural Product Reports, 23, 26-78.

Pivkin, M. V.; Kuznetsova, T. A. and Sova, V. V. (2006). Marine fungi and their metabolites; Dalnauka: Vladivostok. p. 133.

Somei, M. and Yamada, F. (2005). Natural Product Reports, 22, 73-103.

Cuomo, V.; Palomba, I.; Perretti, A.; Guerriero, A.; D’Ambrosio, M. and Pietra, F. (1995). Journal of Marine Biotechnology, 2, 199-204.

Liberra, K. and Lindequist, U. (1995). Marine fungi- a prolific resource of biologically active natural products. Pharmazie 50(H9), 583-588.

Farooq Biabani, M.A. and Laatsch, H. (1998). Journal of Prak. Chemistry-Ztg., 340, 589- 607.

Jensen, P. R. and Fenical, W. (2000). Marine microorganisms and drug discovery: current status and future potential. In: Drugs from the Sea. Fusetani, N. (ed.). Karger, Basel. pp. 6-29.

Liberra, K. and Lindequist, U. (1995). Pharmazie 50(H9), 583-588.

Namikoshi, M. ; Akano, K.; Kobayashi, H.; Koike,Y.; Kitazawa, A.; Rondonuwu, A. B. and Pratasik, S. B. (2002). Journal of Tokyo University of Fisheries, 88, 15-20.

Gloer JB (1997) Environmental and microbial relationship. Springer-Verlag, Berlin, p 249–268

Kohlmeyer J, Volkmann-Kohlmeyer B (1991) Bot Mar 34:1–61

Kubanek J, Whalen KE, Engel S, Kelly SR, Henkel TP, Fenical W (2003) Proc Natl Acad Sci USA 100:6916–6921

Torres YR, Berlinck RGS, Nascimento GGF, Fortier SC, Pessoa C, Moraes MO (2002) Toxicon 40:885–891

Shilpabhat K and Sivarajan M (2006), Journal of Natural Products 60, 906-909.

Fung , L and Lin., G (2003), Deep-Sea Res. II 51, 1759–1768.

Cuomo A and Benjamin (1995), Journal of Marine Biotechnology, 1, 173-189.

Thankur ., R and Stanley., Y (2005), Deep-Sea Res. III 38, 159–178

Pietra,W and Atalla, M., (1997), Malaysian journal of microbiology. 4:14-24

Iwamoto and Khudyakova, Yu., Pivkin, M.V., 2007. Marine fungi as potential producers of antibiotics. 185.

Kustiariyah and Jarman (2011), Mycol. Res, 104:1354-1365

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