Antibacterial activities of different solvent extracts of Neuboldia Levis parts on some gram positive and negative uropathogenic bacterial isolates

Orhue P. O., Momoh ARM, Igumbor E. O, Esumeh F. I.


Considering the assertion that medicinal plants constitute a continuous source of new compounds with potential to act against multi-resistant bacteria, this present investigates the antimicrobial activity of various extracts of the leaves and stem bark of Newbouldia laevis on human urinary tract bacteria isolates. Following standard laboratory procedures, the leaves and back extracts of Newbouldia laevis were studied on Gram positive bacteria (Staphylococcus aureus) and two strains of Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The degree of antibiotic potentials varies with the extraction solvents (water, 1%HCL, ethanolic, acetone and petroleum ether) but not with the parts of the plant. S. aureus and E.coli were more sensitive to Neuboldia levis leaves and bark than P. aeruginosa. Compared to the five extraction solvents, leaf and bark extracts of Neuboldia levis in acetone and petroleum ether showed the best antimicrobial potentials. Neuboldia levis leaf and back extracts demonstrated bactericidal potential against both gram-positive and gram-negative bacteria and could be useful in the inhibition of human urinary tract biotic bacterium.


Key words: Herbs, Neuboldia levis, Antimicrobial, Extraction solvents.

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