Antibacterial activity of selective plant extracts against urinary tract infection causing organisms

Sathya Jagadeesan, Vidhya Natarajan, Rajitha. E. Vijayan


Bacterial pathogens have evolved numerous defense mechanisms against antimicrobial agents; hence resistance to old and newly produced drugs is on the rise. The phenomenon of antibiotic resistance exhibited by the pathogenic microorganisms has led to the need for screening of several medicinal plants for their potential antimicrobial activity. Thus the present study was undertaken to investigate the antibacterial activity of 4 medicinal plants against UTI causing isolates. The antibacterial activity of aqueous, ethanol, ethyl acetate, methanol, Petroleum ether, Chloroform, Extracts of Biophythm sensitivum or mukkutty (whole plant was used), Nutmeg (nut of jathikai was used), Aerva Lanata or cheroola (whole plant was used) and Boerrhavia Difffusa or thazhuthama (leaves were used) was determined against 5 UTI isolates. i.e. Escherechia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus aureus, streptococci viridians, by disc diffusion method. Our studies concluded that crude extracts of the selected plants especially the Ethanol, Methanol, Ethyl acetate extracts exhibited significant activity against UTI pathogens. It can be concluded that these plants can be used to discover natural products that may serve as lead for the development of new pharmaceuticals addressing the major therapeutic needs.


Key words: Urinary tract infection (UTI), Medicinal plants, Antibacterial activity, Disc diffusion assay.

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